Neuroanatomy, Pain and Psychopathology

Team leaders : Michel Barrot, Ipek Yalcin



Our researches concern chronic pain, with a focus on neuropathic pain that arises as a consequence of a lesion or disease of the nervous system. We are studying its treatments, in particular by antidepressant drugs, as well as its affective and anxio-depressive consequences. We also have strong expertise in neuroanatomy, and are studying brain circuits underlying the various components of pain, of emotions and of the control of aminergic systems.



Team projects



Members

Researchers / Professors / Assistant Professors

Michel Barrot

(DR CNRS)

Pierre-Eric Lutz

(CR CNRS)

Jennifer Kaufling
(CR CNRS)

Email

Dominique Massotte

(CR CNRS)

Marie-José Freund-Mercier

(PRem Unistra)

André Muller

(PRem Unistra)

Eric Salvat

(PH HUS)

Pierre Veinante

(PR Unistra)

Ipek Yalcin

(CR CNRS)

Post-docs / PhD students

Heba Elseedy

(Post-doc)

Beyza Ayazgok

(Post-doc)

Léa Becker

(PhD student)

Marion Gaborit

(PhD student)

Han Lu

(PhD student)

Sarah Journée

(PhD student)

Anil Joshi

(PhD student)

Camille Falconnier

(PhD student)

Baptiste Letellier

(PhD student)

Muzeyyen Ugur

(PhD student)

Pierre-Alexis Derrien

(PhD student)

Engineers / Technicians

Mélanie Kremer

(IR CNRS)

Elisabeth Waltisperger

(IE CNRS)

Pierre Hener

(IE CNRS)

Robin Waegaert

(IE CDD)


Selected publications

Kremer M, Yalcin I, Goumon Y, Wurtz X, Nexon L, Daniel D, Megat S, Ceredig RA, Ernst C, Turecki G, Chavant V, Theroux JF, Lacaud A, Joganah LE, Lelievre V, Massotte D, Lutz PE, Gilsbach R, Salvat E, Barrot M (2018) A dual noradrenergic mechanism for the relief of neuropathic allodynia by the antidepressant drugs duloxetine and amitriptyline. J Neurosci 38:9934-9954.

Sellmeijer J, Mathis V, Hugel S, Li XH, Song Q, Chen QY, Barthas F, Lutz PE, Karatas M, Luthi A, Veinante P, Aertsen A, Barrot M, Zhuo M, Yalcin I (2018) Hyperactivity of anterior cingulate cortex areas 24a/24b drives chronic pain-induced depression. J Neurosci 38:3102-3115.