The French National Centre for Scientific Research

Physiology of Neural Networks

Team leader : Philippe ISOPE

Research in our team is focused on the understanding of synaptic properties underlying functional organization in neuronal microcircuits. Our main goal is to identify operational modes of normal and pathological information processing in the cerebellum, olfactory bulb and spinal cord. We combine different types of technique, including in vitro and in vivo electrophysiology, molecular biology, two photon imaging and optogenetic.

Open post-doc position: Spatiotemporal information processing in the rodent cerebellum in vitro (Electrophysiology, 1P and 2P imaging).
Contact philippe.isope at

Team projects


Researchers / Professors

Matilde Cordero-Erausquin

Didier Desaintjan

Frederic Doussau

Bernard Poulain

Philippe Isope


Aline Huber

Ph.D. Students/Postdoctoral fellow

Charlotte Bichara
Ph.D. student

Theo Rossi
Ph.D. student

Federica Lareno-Faccini
Ph.D. student

Ludovic Spaeth
Postdoctoral fellow

Théo Gagneux
Ph.D. student

Gilles Delbecq
Ph.D. student

Most recent publications

Dorgans K, Demais V, Bailly Y, Poulain B, Isope P, Doussau F. Short-term plasticity at cerebellar granule cell to molecular layer interneuron synapses expands information processing. Elife. 2019 May 13;8. pii: e41586. doi:10.7554/eLife.41586.

Özcan OO, Wang X, Binda F, Dorgans K, De Zeeuw CI, Gao Z, Aertsen A, Kumar A, Isope P. Differential Coding Strategies in Glutamatergic and GABAergic Neurons in the Medial Cerebellar Nucleus. J Neurosci. 2020 Jan 2;40(1):159-170.


The French National Centre for Scientific Research