The French National Centre for Scientific Research


Neuroanatomy of brain circuits

Project leader : Pierre VEINANTE


The normal functioning of the brain relies on an extremely complex anatomical organization, in which a multitude of neuronal subtypes establishes specific connections between the different structures. Pathologies such as chronic pain, mood or emotional disorders, are mostly associated with subtle morphofunctional dysfunctions, rather than with large changes in a given structure.

Through multiple morphofunctional approaches in rodents (neuronal tract-tracing, histochemistry, immuno-fluorescence…), we aim at (1) defining the connectomes of the keys structures pertinent for the team’s projects (cingulate cortex, amygdala, tVTA, hypothalamus…), (2) identifying the connections contributing to painful and affective symptoms and (3) characterizing, at cellular level, the morphological and neurochemical changes occurring in models of chronic pain and mood disorders.



Members

Pierre Veinante
(Professor)
 
Pierre Hener
(Study engineer, IE)
 



Publications choisies

Ugur M, Doridot S, la Fleur SE, Veinante P, Massotte D (2021) Connections of the mouse subfornical region of the lateral hypothalamus (LHsf). Brain Structure & Function 226:2431–2458

Ye J, Veinante P (2019) Cell-type specific parallel circuits in the bed nucleus of the stria terminalis and the central nucleus of the amygdala of the mouse. Brain Structure & Function 224:1067-1085

Fillinger C, Yalcin I, Barrot M, Veinante P (2018) Efferents of anterior cingulate areas 24a and 24b and midcingulate areas 24a’ and 24b’ in the mouse. Brain Structure & Function 223:1747-1778

Fillinger C, Yalcin, Barrot M, Veinante P (2017) Afferents to anterior cingulate areas 24a and 24b and midcingulate areas 24a’ and 24b’ in the mouse. Brain Structure & Function 222:1509-1532

 


 
The French National Centre for Scientific Research